Aloe vera may also interact with other medications such as anticoagulant and anti-diabetic medication but more information is needed. As aloe vera can increase how quickly things move through the GI tract, it generally isn't recommended to take at the same time as other oral medications. Long-term use of large amounts of aloe latex might cause diarrhea, kidney problems, blood in the urine, low potassium, muscle weakness, weight loss, … Impact of Aloe Vera Juice on Medicines that are Metabolized by the Enzyme CYP3A4: According to the reports of the MSKCC, Aloe vera is an important factor which hinders the actions of the CYP3A4 enzyme and based on the magazine, “Pharmacy Times”, nearly 50 percent of all medicines present in the market get broken down by this particular enzyme. Usually avoid combinations; use it only under special circumstances. Aloe is a popular over the counter supplement/topical product that is used for a wide range of conditions including: Aloe products are generally extracted from the leaf of the cactus like plant and contain many different active constituents. Always talk to your doctor before mixing aloe vera with any medications. When taking Aloe Vera internally, you must know that it can interact with certain prescription medications. Thank you. Some mixtures of medications can lead to serious and even fatal consequences. Don't take aloe latex and digoxin together. Keywords: Aloe ferox, Aloe marlothii, Aloe vera, efflux, herb-drug interaction, in vitro transport INTRODUCTION Drugs crossing the intestinal epithelium membrane by passive diffusion may be substrates for efflux transporters that extrude compounds back into the gastro-intestinal lumen from within the epithelial cells. 2. [50] It has been stated that use of Aloe A total of 45 drugs are known to interact with The study is created by eHealthMe based on reports of 8 people who take Lansoprazole and Aloe vera from the FDA, and is updated regularly. The anthraquinones contained in aloe vera products are the constituents thought to have the laxative effects in individuals. Minimally clinically significant. Diarrhea is another side effect of consuming aloe vera juice. The perceived benefits of prescribing Aloe vera for OA may be twofold: it has utility as an anti-inflammatory agent and also as a prophylactic against the gastrointestinal irritant effects of non-steroidal anti-inflammatory drugs (NSAIDs). Oral use of aloe might also slow blood clotting. Reports of drug interactions with aloe vera latex include a list of drugs such as diuretics, steroids, and digoxin. The dried latex from the inner lining of the aloe vera leaf is used as an oral laxative. As with any alternative medicine please consult your health provider for treatment, correct dosage, benefits and risk factors. Low potassium might increase the side effects of digoxin. Aloe juice is most commonly taken to treat constipation. Gostaríamos de exibir a descriçãoaqui, mas o site que você está não nos permite. In fact, aloe vera juice can actually be harmful to people with certain medical conditions. I have a cold and the doc prescribed me hycodan. However, taking aloe vera by mouth is known to have significant stimulant laxative effects, which could potentially alter how oral drugs taken at the same time are absorbed. Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of the Q+A website PharmacistAnswers.com. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Aloe gel specifically is obtained from the 'mucilaginous' plant cells in the center of the leaf. Right then, without further ado, let’s get right into 10 Best Aloe Vera Juices 1. When taken orally as a juice or dietary supplement, aloe vera's laxative effects can help ease constipation. Drug interactions and 21 reactions for Aloe Vera (Gel, Juice, Leaf). Aloe vera juice can also interact with sevoflurane (used as anesthesia during surgery) (52). Digoxin: Due to potential electrolyte depletion (e.g. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. ALOE VERA / KUMARI (Aloe vera babadensis): Aloe Vera may have blood-glucose-lowering properties and may therefore be expected to interact with conventional drugs that have the same effect. A laboratory study showed that the plant juice of Aloe vera inhibits the CYP3A4 and CYP2D6 enzymes which may affect the intracellular concentration of drugs metabolized by these enzymes. Aloe Vera also appears to enhance the absorption of some vitamins. Aloe latex can cause some side effects such as stomach pain and cramps. So, monitor your dose of aloe vera and consider healthcare professional in case you notice this side effect of aloe vera. Aloe vera is a succulent plant that’s used in traditional medicine. Common interactions include pulmonary oedema among females and dizziness among males. aloe vera. Digoxin (Lanoxin). Type in a drug name to check for interactions with aloe vera. aloe + arsenic trioxide use alternative or monitor potassium w/ aloe laxative doses: combo may incr. 3. The clear gel from its leaves can be put on the skin as a moisturizer and to treat burns. Find everything you need to know about Aloe Vera Topical (Coats Aloe), including what it is used for, warnings, reviews, side effects, and interactions. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Oral aloe products are generally obtained from a different part of the aloe plant leaf than the aloe gel. risk of hypokalemia, QT prolongation, cardiac arrhythmias (additive effects) Moderately clinically significant. Could my husband drink aloe Vera juice while taking omeprazole? He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Neatly poured into 16.9 ounce bottles, the OKF Farmer’s Aloe Vera drinks come in five different flavors. This side effect can occur due to couple of reasons like the quality of the aloe vera juice, over dosage of juice, extra additives present in the juice, etc. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. As with all over the counter supplements, it is important to let your doctor know if you plan on taking them so you can be appropriately monitored. Aloe latex, like aloe gel, contains the numerous active components. He is also taking losartan, rosuvastatin, aspirin, levothyroxine and a multi vitamin. In our latest question and answer, the pharmacist discusses whether or not aloe vera juice has any drug interactions. Aloe vera juice is touted as a panacea for a long list of ailments from acne to digestive issues, but research doesn’t back the claims. Proponents claim that aloe vera can even speed the healing of wounds and reduce the severity of psoriasis. OKF Farmers – Aloe Vera Drink Flavored Variety Pack. In regard to drug interactions with oral aloe products, there isn't much data to indicate any major interactions. Aloe juice comes from the green part of the aloe leaf located just below the skin and it surrounds the gel. Top Picks. potassium) from the laxative effects of aloe vera, there are potential interactions with drugs like digoxin. Aloe contains two types of substances in its leaf, including a clear gel and a yellowish liquid called aloe juice or latex. Common side effects of aloe include: Diarrhea, kidney problems, blood in the urine, low potassium, muscle weakness, weight loss, and heart disturbances (long-term use at high doses) This document does not contain all possible side effects and others may occur. T wenty-four hours after the juice consumpti on, the man sta rted to have rash on h is legs and a mi ld arthr algia of potassium) from the laxative effects of aloe vera, there are potential interactions with drugs … Highly clinically significant. juice extracted from four to ve leaets o f Aloe vera. Drug Interaction: If you are on some specific medications, then you need to talk to your doctor before consuming aloe vera juice. View interaction reports for aloe vera and the medicines listed below. It may also decrease the efficacy of several diabetes medications and cause the potassium levels to deteriorate if consumed with water pills or diuretics. If you are taking any drug that is considered a substrate of Cytochrome P450 3A4 and CYP2D6, do not drink aloe vera juice. You might also like: What are the Benefits of aloe vera gel for natural hair. Aloe latex can cause some side effects such as stomach pain and cramps. Drug interactions are reported among people who take Lansoprazole and Aloe vera. Learn more about Aloe Vera … In terms of drug interactions, oral aloe vera has a stimulant laxative effect and can increase the speed at which medications and food move through the GI tract. The juice exerts anti-platelet effects and may interfere with drugs like warfarin (used as a blood thinner) (53). He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Drug Interactions. For people with allergies to Aloe vera, skin reactions may include contact dermatitis with mild redness and itching, difficulty with breathing, or swelling of the face, lips, tongue, or throat. Therefore, aloe vera should ideally not be taken at the same time as oral medications. Also, aloe latex has been shown to influence the effectiveness of blood pressure medications, potassium-sparing drugs, and medications used in diabetes. Oh yes, and we’ll also give you a top 10 list of the best Aloe Vera-based juices! As a general recommendation with laxatives, oral medications should be: Below are some other potential drug interactions based on studies and case reports: The evidence behind the above interactions are lacking and more evidence is needed to make a better determination of aloe vera drug interactions. Anticoagulants and anti-platelet drugs, herbs and supplements. Is it safe to take Anxietex  if I am taking medicine for high blood pressure, Metoprolol Succ Er 100 mg & Losartan Potassium 50 mg ? Anticoagulant Drugs: Aloe vera may decrease certain clotting factors, increasing the risk of bleeding when used with anticoagulant/anti-platelet drugs. It has a soothing effect that may aid in the treatment of genital herpes, poison oak, poison ivy, and radiation-induced skin reactions. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. We comply with the HONcode standard for trustworthy health information -, Fish Oil (omega-3 polyunsaturated fatty acids), Glucosamine & Chondroitin with MSM (chondroitin / glucosamine / methylsulfonylmethane), Omega-3 (omega-3 polyunsaturated fatty acids), Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus). Digoxin: Due to potential electrolyte depletion (e.g. Available for Android and iOS devices. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Despite being used as arthritis treatment for centuries (Yoo et al, 2008), evidence of effectiveness of Aloe vera is anecdotal or from small studies. If taking extended release medications, oral aloe products aren't recommended. Some people drink aloe vera juice as a laxative (something that helps you poop). 13. Aloe vera may be prepared as a lotion, gel, soap or cosmetics product for use on skin as a topical medication. And 100 mg spironolatane twice a day. Drug interactions are reported among people who take Aloe vera and Metformin. Risk and consider healthcare professional in case you notice this side effect of aloe leaf! Also decrease the efficacy of several diabetes medications and cause the potassium levels aloe vera juice drug interactions... Of some vitamins water pills or diuretics should ideally not be taken at the same as... 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